Actor
- The New Adventures of Old Christine The Old Maid of Honor (2009) .... Barb
- The New Adventures of Old Christine Notes on a 7th Grade Scandal (2009) .... Barb
- The Jay Leno Show Episode #1.39 (2009) .... Herself
- The New Adventures of Old Christine Everyone Says I Love You Except Ritchie (2008) .... Barbara 'Barb' Daran (credit only)
- The New Adventures of Old Christine So You Think You Can Date (2008) .... Barb
- The New Adventures of Old Christine Self-Esteem Tempura (2008) .... Barb (credit only)
- The New Adventures of Old Christine Burning Down the House (2008) .... Barb
- The New Adventures of Old Christine Snakes on a Date (2008) .... Barb
- The New Adventures of Old Christine Between a Rock and a Hard Place (2008) .... Barb
- The New Adventures of Old Christine The Happy Couple (2008) .... Barb
- The New Adventures of Old Christine Unidentified Funk (2008) .... Barb
- The New Adventures of Old Christine Happy Endings (2008) .... Barb
- The New Adventures of Old Christine Guess Who's Not Coming to Dinner? (2008) .... Barb
- The New Adventures of Old Christine A Decent Proposal (2008) .... Barb
- License to Wed (2007) .... Doctor (uncredited)
- Evan Almighty (2007) .... Rita
- Corazón de... Episode dated 10 January 2007 (2007) .... Herself (archive footage)
- Back at the Barnyard Farmer Takes a Woman (2007) .... Bessy the Cow (voice)
- Back at the Barnyard The Right Cow (2007) .... Bessy the Cow (voice)
- Wanda Sykes: Sick and Tired (2006) .... Herself
- Barnyard (2006) .... Bessy the Cow (voice)
- Clerks II (2006) .... Wife in Mooby's
- My Super Ex-Girlfriend (2006) .... Carla Dunkirk
- Over the Hedge (2006) .... Stella (voice)
- CondomNation (2006) .... Linda
- The New Adventures of Old Christine (2006) .... Barb (43 episodes, 2006-2009)
- Will & Grace Buy, Buy Baby (2006) .... Cricket
- New Year's Eve with Carson Daly (2005) .... Himself - Guest
- Richard Pryor: The Funniest Man Dead or Alive (2005) .... Herself
- Earth to America (2005) .... Herself
- Monster-in-Law (2005) .... Ruby
- Curb Your Enthusiasm The Bowtie (2005) .... Wanda
- Wanda Does It (2004) .... Herself (1 episode, 2004)
- Comedy Central Presents: 100 Greatest Stand-Ups of All Time (2004) .... Herself #70 (archive footage)
- Curb Your Enthusiasm The Surrogate (2004) .... Wanda
- Celebrity Poker Showdown Tournament 2, Game 1 (2004) .... Herself
- Comedy Central Presents: The Commies (2003) .... Herself - Presenter
- Richard Pryor: I Ain't Dead Yet, #*%$#@!! (2003) .... Herself
- Wanda Sykes: Tongue Untied (2003) .... Herself
- Wanda at Large (2003) .... Wanda Mildred Hawkins / ... (9 episodes, 2003)
- Heroes of Comedy: Women on Top (2003) .... Herself
- MTV: Reloaded (2003) .... The Oracle
- MADtv Episode #9.3 (2003) .... Herself
- Chappelle's Show The Best of Chappelle's Show: Volume 2 Mixtape (2003) .... Herself
- 100 Sexiest Artists (2002) .... Herself / interviewed
- Curb Your Enthusiasm The Benadryl Brownie (2002) .... Wanda
- Curb Your Enthusiasm The Terrorist Attack (2002) .... Wanda
- Curb Your Enthusiasm Krazee-Eyez Killa (2002) .... Wanda
- Pootie Tang (2001) .... Biggie Shorty
- Down to Earth (2001) .... Wanda
- Best of the Chris Rock Show: Volume 2 (2001) .... Herself
- Curb Your Enthusiasm The Massage (2001) .... Wanda
- Curb Your Enthusiasm Thor (2001) .... Wanda
- Nutty Professor II: The Klumps (2000) .... Chantal
- Best of the Chris Rock Show (1999) .... Various characters
- Dr. Katz, Professional Therapist Walk for Hunger (1999) .... Herself (voice) (as Wanda Sykes-Hall)
- Comedy Central Presents: The N.Y. Friars Club Roast of Drew Carey (1998) .... Herself
- Tomorrow Night (1998) ....
- HBO Comedy Showcase (1995) ....
- Wanda Sykes: Sick and Tired (2006) .... executive producer
- Wanda Does It (2004) .... executive producer (6 episodes, 2004)
- Wanda at Large (2003) .... producer (19 episodes, 2003)
- The Chris Rock Show (1997) .... consultant (4 episodes, 1997)
- Wanda Sykes: Sick and Tired (2006) .... writer
- Wanda Does It (2004) .... (6 episodes, 2004)
- Wanda Sykes: Tongue Untied (2003) .... writer
- Wanda at Large (2003) .... (19 episodes, 2003)
- The Downer Channel (2001) .... (unknown episodes)
- Best of the Chris Rock Show: Volume 2 (2001) .... writer
- Premium Blend (1997) .... (unknown episodes, 2002-2003)
- The Keenen Ivory Wayans Show (1997) .... (unknown episodes)
- The Chris Rock Show (1997) .... (unknown episodes)


