Actor
- Julie & Julia (2009) .... Julia Child
- Doubt (2009) .... Sister Aloysius Beauvier
- Mamma Mia! (2008) .... Donna Sheridan
- Dirty Tricks (2008) .... Martha Mitchell
- Imaginary Witness: Hollywood and the Holocaust (2007) .... (archive footage)
- Lions for Lambs (2007) .... Janine Roth
- Rendition (2007) .... Corrine Whitman
- Evening (2007) .... Lila Ross
- Dark Matter (2007) .... Joanna Silver
- The Ant Bully (2006) .... Queen (voice)
- The Devil Wears Prada (2006) .... Miranda Priestly
- A Prairie Home Companion (2006) .... Yolanda Johnson
- Boffo! Tinseltown's Bombs and Blockbusters (2006) .... Karen Christence Dinesen Blixen (archive footage) (uncredited)
- Hurricane on the Bayou (2006) .... Narrator
- The Music of Regret (2006) .... The Woman
- Wrestling with Angels: Playwright Tony Kushner (2006) .... Herself
- Prime (2005) .... Lisa Metzger
- Stolen Childhoods (2005) .... Herself - narrator (voice)
- Lemony Snicket's A Series of Unfortunate Events (2004) .... Aunt Josephine
- Monet's Palate: A Gastronomic View from the Gardens of Giverny (2004) .... Narrator
- The Manchurian Candidate (2004) .... Eleanor Shaw
- Stuck on You (2003) .... Herself (uncredited)
- The Hours (2003) .... Clarissa Vaughan
- Adaptation. (2003) .... Susan Orlean
- Artificial Intelligence: AI (2001) .... Blue Mecha (voice)
- "Intimate Portrait" Diane Keaton (2001) .... Herself
- The Papp Project (2001) .... Herself
- Music of the Heart (1999) .... Roberta Guaspari
- Dancing at Lughnasa (1998) .... Kate 'Kit' Mundy
- One True Thing (1998) .... Kate Gulden
- Marvin's Room (1997) .... Lee
- Assignment: Rescue (1997) .... Narrator (voice)
- Before and After (1996) .... Dr. Carolyn Ryan
- The Bridges of Madison County (1995) .... Francesca Johnson
- The Living Sea (1995) .... Narrator (voice)
- The House of the Spirits (1994) .... Clara del Valle Trueba
- A Century of Cinema (1994) .... Herself
- Death Becomes Her (1992) .... Madeline Ashton
- Defending Your Life (1991) .... Julia
- Postcards from the Edge (1990) .... Suzanne Vale
- She-Devil (1989) .... Mary Fisher
- Evil Angels (1988) .... Lindy Chamberlain
- Ironweed (1987) .... Helen Archer
- Heartburn (1986) .... Rachel Samstat
- Out of Africa (1985) .... Karen Blixen
- Plenty (1985) .... Susan Traherne
- Falling in Love (1984) .... Molly Gilmore
- In Our Hands (1984) .... Herself
- Silkwood (1983) .... Karen Silkwood
- Sophie's Choice (1982) .... Sophie Zawistowski
- Still of the Night (1982) .... Brooke Reynolds
- The French Lieutenant's Woman (1981) .... Sarah / Anna
- Kramer vs. Kramer (1979) .... Joanna Kramer
- The Seduction of Joe Tynan (1979) .... Karen Traynor
- Manhattan (1979) .... Jill Davis
- The Deer Hunter (1979) .... Linda
- Everybody Rides the Carousel (1975) .... Stage 6 (voice)


bobgon