Actor
- When We Left Earth: The NASA Missions (2008) .... Narrator (6 episodes, 2008)
- National Memorial Day Parade (2008) .... Himself
- National Memorial Day Concert (2007) .... Himself - Host
- Open Season (2006) .... Shaw (voice)
- Wanderlust (2006) .... Himself (voice)
- AFI's 100 Years... 100 Cheers: America's Most Inspiring Movies (2006) .... Himself
- The March of the Bonus Army (2006) .... Narrator (voice)
- Magnificent Desolation: Walking on the Moon 3D (2005) .... Gene Cernan (voice)
- Tsunami Aid: A Concert of Hope (2005) .... Himself
- The Forgotten (2004) .... Dr. Jack Munce
- CSI: NY (2004) .... Detective Mac Taylor (102 episodes, 2004-2008)
- The Big Bounce (2004) .... Ray Ritchie
- This Old Cub (2004) ....
- Fallen Angel (2003) .... Terry McQuinn
- The Human Stain (2003) .... Nathan Zuckerman
- Hollywood High (2003) .... Himself
- Mission: Space (2003) .... Capcom
- Path to War (2002) .... George Wallace (uncredited)
- Impostor (2002) .... Spencer Olham
- Hideous Man (2002) .... Hideous Man
- Made-Up (2002) .... Duncan Tivey
- A Gentleman's Game (2001) .... Foster Pearse
- Mission to Mars (2000) .... Jim McConnell
- Reindeer Games (2000) .... Gabriel Mercer
- Bruno (2000) .... Dino Battaglia
- CBS Cares (2000) .... Himself (5 episodes, 2004-2008)
- The Green Mile (1999) .... Burt Hammersmith
- The Miracle of 'The Green Mile' (1999) .... Himself
- Being John Malkovich (1999) .... Stage Role (archive footage) (uncredited)
- That Championship Season (1999) .... Tom Daley
- All the Rage (1999) .... Morgan
- Snake Eyes (1998) .... Commander Kevin Dunne
- Sam Shepard: Stalking Himself (1998) .... Himself
- George Wallace (1997) .... George C. Wallace
- Albino Alligator (1997) .... Milo
- Ransom (1996) .... Det. Jimmy Shaker
- Chicago on Stage (1995) .... Himself
- Truman (1995) .... Harry S. Truman
- Apollo 13 (1995) .... Ken Mattingly
- The 67th Annual Academy Awards (1995) .... Himself - Nominee: Best Actor in a Supporting Role
- The Quick and the Dead (1995) .... The Marshal
- The 21st Annual People's Choice Awards (1995) .... Himself
- Frasier The Club (1995) .... Sid (voice)
- Forrest Gump (1994) .... Lt. Dan Taylor
- The Stand (1994) .... Stu Redman
- Through the Eyes of Forrest Gump (1994) .... Himself
- The Stand: The Making of... (1994) .... Himself
- Nyhetsmorgon Filmen 'Forest Gump'/Nyheter och väder (1994) .... Himself
- The Stand The Stand (1994) .... Stu Redman
- The Stand The Betrayal (1994) .... Stu Redman
- The Stand The Dreams (1994) .... Stu Redman
- The Stand The Plague (1994) .... Stu Redman
- Jack the Bear (1993) .... Norman Strick
- Of Mice and Men (1992) .... George Milton
- A Midnight Clear (1992) .... Vance 'Mother' Wilkins
- The Grapes of Wrath (1991) .... Tom Joad
- Hunter Lullaby (1990) .... Lord Tony Rutherford
- The Final Days (1989) .... Richard Ben-Veniste
- My Name Is Bill W. (1989) .... Ebby, Bill's best friend
- Family Secrets (1984) .... Motorcyclist
- Biography The Barrymores (1932) .... Himself - Host / Narrator
- Of Mice and Men (1992) ....
- Miles from Home (1988) ....
- thirtysomething (1987) .... (2 episodes, 1989)
- Crime Story (1986) .... (unknown episodes)
- Crime Story The St. Louis Book of Blues (1986) .... (episode "Fortune in Men's Eyes") (episode "Torello on Trial") (as Gary A. Sinise)
- Brothers at War (2009) .... executive producer
- CSI: NY (2004) .... producer (51 episodes, 2005-2008)
- Impostor (2002) .... producer
- That Championship Season (1999) .... executive producer
- Of Mice and Men (1992) .... producer
- The Grapes of Wrath (1991) .... consultant
- American Playhouse (1982) .... stage director (1 episode, 1984)
- Being John Malkovich (1999) .... acknowledgment
- CSI: NY (2004) .... (2 episodes, 2006-2008)


