Actor
- Buñuel en Hollywood (2000) .... Himself
- The Rat Pack (1998) .... Joe Kennedy
- Love, Cheat & Steal (1993) .... Hamilton Fisk
- The Pirates of Dark Water (1991) .... Additional Voices (21 episodes, 1991-1993)
- RoboCop 2 (1990) .... The Old Man
- John Huston and the Dubliners (1988) .... Himself
- A Waltz Through the Hills (1988) .... Uncle Tom
- The Dead (1987) .... Mr. Browne
- RoboCop (1987) .... The Old Man (as Daniel O'Herlihy)
- Dark Mansions (1986) .... Alexander Drake
- The Whoopee Boys (1986) .... Judge Sternhill
- Murder, She Wrote Stage Struck (1986) .... Alexander Preston
- The Last Starfighter (1984) .... Grig
- The Last Day (1983) ....
- Halloween III: Season of the Witch (1982) .... Conal Cochran
- Death Ray 2000 (1981) .... The Director
- Artemis 81 (1981) .... Dr. Albrecht Von Drachenfels
- Mark Twain: Beneath the Laughter (1979) .... Mark Twain
- A Man Called Sloane (1979) .... The Director (1 episode, 1979)
- Battlestar Galactica Gun on Ice Planet Zero: Part 2 (1978) .... Dr. Ravashol
- Deadly Game (1977) .... Colonel Edward Stryker
- Good Against Evil (1977) .... Father Kemschler
- MacArthur (1977) .... President Franklin D. Roosevelt
- The Quest (1976) .... Mathew Hatcher (2 episodes, 1976)
- Banjo Hackett: Roamin' Free (1976) .... Tip Conaker
- The Quest: The Longest Drive (1976) .... Mathew Hatcher
- The Tamarind Seed (1974) .... Fergus Stephenson
- The Carey Treatment (1972) .... J.D. Randall
- The People (1972) .... Sol Diemus
- Waterloo (1970) .... Marshal Michel Ney
- The Big Cube (1969) .... Charles Winthrop
- 100 Rifles (1969) .... Steven Grimes
- How to Steal the World (1969) .... Prof. David Garrow
- The Long, Hot Summer (1965) .... 'Boss' Will Varner #2 (12 episodes, 1966)
- Fail-Safe (1964) .... Brig. Gen. Warren A. Black
- The Presidency: A Splendid Misery (1964) ....
- The Travels of Jaimie McPheeters (1963) .... 'Doc' Sardius McPheeters (26 episodes, 1963-1964)
- The Travels of Jaimie McPheeters The Day of the Giants (1963) .... 'Doc' Sardius McPheeters
- The Travels of Jaimie McPheeters The Day of the First Suitor (1963) .... 'Doc' Sardius McPheeters
- The Cabinet of Caligari (1962) .... Caligari / Paul
- Bonanza The Artist (1962) .... Matthew Raine
- King of the Roaring 20's - The Story of Arnold Rothstein (1961) .... Phil Butler
- One Foot in Hell (1960) .... Sir Harry Ivers
- A Terrible Beauty (1960) .... Don McGinnis
- The Best of the Post (1960) .... Doctor / ... (2 episodes, 1961)
- The Young Land (1959) .... Judge Millard Isham
- Imitation of Life (1959) .... David Edwards
- Home Before Dark (1959) .... Arnold Bronn
- That Woman Opposite (1957) .... Dermot Kinross
- The Purple Mask (1955) .... Brisquet
- The Virgin Queen (1955) .... Lord Derry
- Hunters of the Deep (1955) .... Narrator
- Bengal Brigade (1954) .... Capt. Ronald Blaine (as Daniel O'Herlihy)
- The Black Shield of Falworth (1954) .... Prince Hal of Wales (as Daniel O'Herlihy)
- Robinson Crusoe (1954) .... Robinson Crusoe (as Daniel O'Herlihy)
- Sword of Venus (1953) .... Danglars
- Invasion USA (1952) .... Mr. Ohman
- Operation Secret (1952) .... Duncan
- Actor's and Sin (1952) .... Alfred O'Shea / Narrator (Actor's Blood sequence)
- At Sword's Point (1952) .... Aramis
- The Highwayman (1951) .... Robin
- The Blue Veil (1951) .... Hugh Williams
- Soldiers Three (1951) .... Sgt.Murphy
- The Last Half Hour: The Mayerling Story (1951) .... Rudolf, Crown Prince of Austria
- Lux Video Theatre (1950) .... Alan / ... (3 episodes, 1955)
- Macbeth (1950) .... Macduff
- The Iroquois Trail (1950) .... Lt. Blakely
- Larceny (1948) .... Duke
- Kidnapped (1948) .... Alan Breck
- Hungry Hill (1947) .... Harry Brodrick
- Odd Man Out (1947) .... Nolan
- Macbeth (1950) .... set designer (uncredited)