Actor
- Furry Vengeance (2010) .... Dan Sanders
- Extraordinary Measures (2010) .... John Crowley
- This Side of the Looking Glass (2010) .... Ben (rumored)
- G.I. Joe: The Rise of Cobra (2009) .... Sgt. Stone (uncredited)
- Inkheart (2009) .... Mo 'Silvertongue' Folchart
- The 14th Annual Critics' Choice Awards (2009) .... Himself - Presenter
- The Mummy: Tomb of the Dragon Emperor (2008) .... Richard 'Rick' O'Connell
- Journey to the Center of the Earth (2008) .... Prof. Trevor Anderson
- 2008 MTV Movie Awards (2008) .... Himself
- Singularity (2008) ....
- HBO First Look The Mummy: Tomb of the Dragon Emperor (2008) .... Himself
- The Air I Breathe (2007) .... Pleasure
- The Last Time (2007) .... Jamie
- [scrubs] My Night to Remember (2007) .... Ben Sullivan (archive footage) (uncredited)
- HBO First Look Looney Tunes: Back in Action (2007) .... Himself
- ...So Goes the Nation (2006) .... Himself
- Journey to the End of the Night (2006) .... Paul
- Crash (2005) .... Rick Cabot
- Beach Bunny (2005) .... Beach Bum (voice)
- King of the Hill Gone with the Windstorm (2005) .... Irv Bennett / Jimmy Beardon (voice)
- 101 Most Unforgettable SNL Moments (2004) .... Himself (archive footage)
- Revenge of the Mummy: The Ride (2004) .... Rick O'Connell
- Jessica's Crush (2004) .... Himself
- Scrubs My Screwup (2004) .... Ben Sullivan
- The Osbourne Family Christmas Special (2003) .... Himself
- Looney Tunes: Back in Action (2003) .... DJ Drake / Himself / Voice of Tasmanian Devil and She-Devil
- Dickie Roberts: Former Child Star (2003) .... Himself (uncredited)
- The Quiet American (2003) .... Alden Pyle
- Still Perfect: 20 Unforgettable Photographs (2002) ....
- [scrubs] My Occurrence (2002) .... Ben Sullivan
- [scrubs] My Hero (2002) .... Ben Sullivan
- The Mummy Returns (2001) .... Richard 'Rick' O'Connell
- Monkeybone (2001) .... Stu Miley
- Bedazzled (2000) .... Elliot Richards / Jefe / Mary
- Sinbad: Beyond the Veil of Mists (2000) .... Sinbad (voice)
- Saturday Night Live Rob Lowe/Eminem (2000) .... Himself (uncredited)
- King of the Hill Peggy Makes the Big Leagues (2000) .... David Kalaiki-Alii (voice)
- Saturday Night Live: 25th Anniversary (1999) .... Himself - Audience Member (uncredited)
- Dudley Do-Right (1999) .... Dudley Do-Right
- The Mummy (1999) .... Richard 'Rick' O'Connell
- Blast from the Past (1999) .... Adam
- Mummies: The Real Story (1999) .... Narrator
- Gods and Monsters (1998) .... Clayton Boone
- Still Breathing (1998) .... Fletcher McBracken
- George of the Jungle (1997) .... George of the Jungle
- The Twilight of the Golds (1997) .... David Gold
- Glory Daze (1996) .... Doug
- The Passion of Darkly Noon (1996) .... Darkly Noon
- Mrs. Winterbourne (1996) .... Bill / Hugh Winterbourne
- Kids in the Hall: Brain Candy (1996) .... Cameo appearance (placebo patient) (uncredited)
- Now and Then (1995) .... Vietnam Veteran (uncredited)
- The Scout (1994) .... Steve Nebraska
- In the Army Now (1994) .... Link (uncredited)
- Airheads (1994) .... Chester 'Chazz' Darvey
- With Honors (1994) .... Montgomery 'Monty' Kessler
- Younger and Younger (1993) .... Winston Younger
- Twenty Bucks (1993) .... Sam Mastrewski
- Son in Law (1993) .... Link (uncredited)
- School Ties (1992) .... David Greene
- Encino Man (1992) .... Link
- Guilty Until Proven Innocent (1991) .... Bobby McLaughlin
- Child of Darkness, Child of Light (1991) .... John's friend
- Dogfight (1991) .... Sailor #1 (as Brendon Fraser)
- My Old School (1991) ....
- Furry Vengeance (2010) .... executive producer
- Journey to the Center of the Earth (2008) .... executive producer
- [scrubs] My Occurrence (2002) .... still photographer
- Anatomy of a Scene (2001) .... special thanks (1 episode)

